Polycystic Ovarian Disease: Presence of many minute cysts in the ovaries, by excess production of androgens, and by
infrequent periods (obliomenorrhoea) or absence of periods (amenorrhoea).

Failure to ovulate (20% of cases): is common due to stress, hormonal imbalances, and various disorders.

Age: After the age of 30 the quality of the eggs begins to diminish, and it becomes harder to become pregnant and carry a fetus to term.

Pelvic inflammation (10% of cases): Blocked or damaged fallopian tubes due to STD, miscarriages, abortions, childbirth, or an intrauterine device.

Uterine Fibroids: It occurs in 40% of women and can interfere with implantation or growth.

Endometriosis (5% of cases): The tissue, which lines the uterus (endometrium), grows outside of the uterus.

Prenatal Exposure to Diethylstilbestrol (DES): DES is a synthetic estrogen given to some women who were deemed at risk for miscarriage during the 1950's and 1960's. Women whose mothers took DES while pregnant with them are at high risk for organ disorders.

Pelvic Adhesions: Caused by surgery or infection, it occurs when scar tissue forms between two or more internal organs.

Immunological Infertility: The woman's system produces antisperm antibodies, which destroy her partner's sperm.